United States securities and exchange commission logo July 2, 2020 Mike Shapiro Chief Financial Officer Option Care Health, Inc. 3000 Lakeside Drive Suite 300N Bannockburn, Illinois 60015 Re: Option Care Health, Inc. Registration Statement on Form S-3 Filed June 26, 2020 File No. 333-239504 Dear Mr. Shapiro: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Abby Adams at (202) 551-6902 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences